Chlorhexidine gluconate is a bis-biguanide antimicrobial used as an oral rinse or local antiseptic. It is most often used as a mouthwash with its mechanism of action being the lysis of bacterial membranes. Chlorhexidine gluconate is often used in the treatment of gingivitis, a disorder of the gums that causes the tissue to become inflamed and bleed. Used in conjunction with proper oral care, regular brushing and flossing, this drug can help in the reduction of gingivitis related inflammation and bleeding by reducing the number of bacteria in and around the affected tissues. The dosage and frequency of use may be adjusted by a dental practitioner depending upon the severity of the gum disease and any other underlying factors. Though chlorhexidine gluconate is a very effective treatment for gingivitis, it does come with possible side effects including alteration of the user’s sense of taste, an increase in tartar formation, and staining of the teeth, mouth, and tongue.