Biointegration is the bonding of living tissue to the surface of a biomaterial or implant, independent of any mechanical interlocking mechanism. It is often used to describe the bond to hydroxyapatite-coated dental implants. Biointegration is essential to the success and longevity of the implant. Once the fixture has been placed in the bone, new bone cells should begin to grow around it, bonding with the fixture surface. This allows the fixture to integrate into the surrounding bone to provide a stable foundation for the abutment and implant. Successful biointegration can depend on several factors including the quality and quantity of existing bone around the implant, the structure and material of the fixture and implant, when loading of the implant takes place, and the oral health and hygiene of the patient. Patients who experience successful biointegration generally have a low risk of implant failure after the first year following the procedure.